Unexpected Synchronous Diagnosis of Papillary Thyroid Carcinoma in a Patient with Lower Lip Squamous Cell Carcinoma

Veysel Murat Işık, Mert Çalış, Nezih Sungur, Mustafa Gürhan Ulusoy, Uğur Koçer

Özet


The presentation of differentiated thyroid carcinoma occurring as a second primary associated with head and neck squamous cell carcinoma
is quite unusual. Here, we present an unexpected synchronous diagnosis of two independent head and neck malignancies. A 78‑year‑old
male with a rapidly growing, firm, and ulcerated lesion on the lower lip was referred to our clinic. Positron emission tomography‑computed
tomography scan performed for systemic screening demonstrated a dense hypermetabolic activity located in the right thyroid lobe, suggesting a
second malignancy. Fine‑needle aspiration cytology of the right thyroid gland performed to differentiate the presence of a metastatic lesion, or
primary thyroid cancer was compatible with malign cytology related to papillary thyroid carcinoma. Multiple malignancies may be diagnosed
synchronously in the head and neck region and these patients with multiple malignant lesions should be evaluated carefully before being
accepted as metastatic.

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Referanslar


Hasson O. Squamous cell carcinoma of the lower lip. J Oral Maxillofac Surg. 2008;66(6):1259–62.

Casal D, Carmo L, Melancia T, Zagalo C, Cid O, Rosa-Santos J. Lip cancer: a 5-year review in a tertiary referral centre. J Plast Reconstr Aesthet Surg. 2010;63(12):2040–5.

Pitman KT, Johnson JT, Myers EN. Papillary thyroid carcinoma associated with squamous cell carcinoma of the head and neck: significance and treatment. Am J Otolaryngol. 1996;17(3):190–6.

Black APB, Human MRC, Unit I. The role of p53 in the immunobiology of cutaneous squamous cell carcinoma. Clin Exp Immunol. 2003;132(3):379–84.

Castaldi P, Leccisotti L, Bussu F, Rufini V. Role of 18 F-FDG PET-CT in head and neck squamous cell carcinoma. Acta Otorhinolaryngol Ital. 2013;33(1):1–8.

Clark RL, Hickey RC, Butler JJ, Ibanez ML, Ballantyne AJ. Thyroid cancer discovered incidentally during treatment of an unrelated head and neck cancer: review of 16 cases. Ann Surg. 1966;163(5):665–71.

Vassilopoulou-Sellin R, Weber RS. Metastatic thyroid cancer as an incidental finding during neck dissection: significance and management. Head Neck. 1992;14(6):459–63.




Online ISSN:2528-8644
Basılı ISSN:1300-6878 (önceki)

Türk Plastik Rekonstrüktif ve Estetik Cerrahi Dergisi (Turk J Plast Surg),
Türk Plastik Rekonstrüktif ve Estetik Cerrahi Derneği'nin, Estetik Plastik Cerrahi Derneği'nin, Türkiye Interplast Derneği'nin ve Çene Yüz Cerrahları Derneği'nin yayın organıdır.